ISDA: 9OEK

Deposition Date 2025-04-28

Release Date 2026-09-02

Last Version Date 2026-09-02

Entry Detail

PDB ID:

9OEK

Keywords:

PROTEIN FIBRIL

Title:

amyloid fibril of recombinant transforming growth factor beta induced protein FAS1-4 domain with V624M mutation

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.24 Å

Aggregation State:

FILAMENT

Reconstruction Method:

HELICAL

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Transforming growth factor-be
Gene (Uniprot):TGFBI
Mutagens:V624M
Chain IDs:A, B, C, D, E, F, G, H, I, J
Chain Length:156
Number of Molecules:10
Biological Source:Homo sapiens

UniProt ID:Q15582 Pfam ID:PF02469

Ligand Molecules

Primary Citation

Structure of TGFBIp amyloid fibril driven by a corneal dystrophy-causing mutation

Jiang, Y.X, Sawaya, M.R, Salwinski, L, Ge, P, Wang, C, Hu, C.J, Hernandez, H, Boyer, D.R, Melo, F, Eisenberg, D.S.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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