ISDA: 9O18

Deposition Date 2025-04-03

Release Date 2026-09-09

Last Version Date 2026-09-09

Entry Detail

PDB ID:

9O18

Keywords:

IMMUNE SYSTEM

Title:

Fab1504 in complex with the C-terminal alpha-TSR domain of the P. falciparum circumsporozoite protein

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Plasmodium falciparum (Taxon ID: 5833)

Expression System(s):

Cricetulus griseus

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.20 Å

R-Value Free:

0.24

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

P 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Circumsporozoite protein
Gene (Uniprot):CSP
Chain IDs:C (auth: G), F (auth: C), I (auth: F), L (auth: K)
Chain Length:73
Number of Molecules:4
Biological Source:Plasmodium falciparum

UniProt ID:Q7K740 Pfam ID:PF00090

Polymer Type:polypeptide(L)
Molecule:Fab1504 Heavy Chain
Chain IDs:A (auth: H), D (auth: A), G (auth: D), J (auth: I)
Chain Length:230
Number of Molecules:4
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Fab1504 Light Chain
Chain IDs:B (auth: L), E (auth: B), H (auth: E), K (auth: J)
Chain Length:214
Number of Molecules:4
Biological Source:Homo sapiens

Primary Citation

Fab1504 in complex with the C-terminal alpha-TSR domain of the P. falciparum circumsporozoite protein

Moskovitz, R, Wilson, I.A.Show

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