ISDA: 9NQX

Deposition Date 2025-03-13

Release Date 2026-07-29

Last Version Date 2026-07-29

Entry Detail

PDB ID:

9NQX

Keywords:

HYDROLASE

Title:

Human Neu2 Sialidase Engineered for Better Half-Life

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.89 Å

R-Value Free:

0.27

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

P 32

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Sialidase-2
Gene (Uniprot):NEU2
Chain IDs:A, B, C
Chain Length:374
Number of Molecules:3
Biological Source:Homo sapiens

UniProt ID:Q9Y3R4 Pfam ID:PF13088 EC:3.2.1.18

Ligand Molecules

DAN

EDO

Primary Citation

Human Neu2 Sialidase Engineered for Better Half-Life

Kemp, M.T, Cao, L, Shelke, S, Turner, A, Peng, L.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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