9NPR image
Deposition Date 2025-03-11
Release Date 2025-12-31
Last Version Date 2026-07-15
Entry Detail
PDB ID:
9NPR
Keywords:
Title:
RAVV glycoprotein in complex with hNPC1-C
Biological Source:
Source Organism(s):
Expression System(s):
Method Details:
Experimental Method:
Resolution:
3.53 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Envelope glycoprotein RAVV GP
Gene (Uniprot):GP
Chain IDs:D (auth: A), F (auth: B), H (auth: C)
Chain Length:256
Number of Molecules:3
Biological Source:Ravn virus - Ravn, Kenya, 1987
Polymer Type:polypeptide(L)
Molecule:Envelope glycoprotein RAVV GP
Gene (Uniprot):GP
Chain IDs:E (auth: D), G (auth: E), I (auth: F)
Chain Length:247
Number of Molecules:3
Biological Source:Ravn virus - Ravn, Kenya, 1987
Polymer Type:polypeptide(L)
Molecule:NPC intracellular cholesterol
Gene (Uniprot):NPC1
Chain IDs:A (auth: G), B (auth: H), C (auth: I)
Chain Length:280
Number of Molecules:3
Biological Source:Homo sapiens
Ligand Molecules
Primary Citation
Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor.
Nature 653 621 626 (2026)
PMID: 41813895 DOI: 10.1038/s41586-026-10240-0
Primary Citation of related structures
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