ISDA: 9NI1

Deposition Date 2025-02-25

Release Date 2026-09-09

Last Version Date 2026-09-09

Entry Detail

PDB ID:

9NI1

Keywords:

IMMUNE SYSTEM

Title:

Fab389 in complex with the C-terminal alpha-TSR domain of the P. falciparum circumsporozoite protein

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Plasmodium falciparum 3D7 (Taxon ID: 36329)

Expression System(s):

Cricetulus griseus, Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.75 Å

R-Value Free:

0.21

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

C 1 2 1

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Circumsporozoite protein
Gene (Uniprot):CSP
Chain IDs:C, E (auth: B)
Chain Length:73
Number of Molecules:2
Biological Source:Plasmodium falciparum 3D7

UniProt ID:Q7K740 Pfam ID:PF00090

Polymer Type:polypeptide(L)
Molecule:Fab389 heavy chain
Chain IDs:A (auth: H), D (auth: A)
Chain Length:227
Number of Molecules:2
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Fab389 light chain
Chain IDs:B (auth: L), F (auth: D)
Chain Length:215
Number of Molecules:2
Biological Source:Homo sapiens

Ligand Molecules