ISDA: 9NDM

Deposition Date 2025-02-18

Release Date 2026-09-09

Last Version Date 2026-09-09

Entry Detail

PDB ID:

9NDM

Keywords:

IMMUNE SYSTEM

Title:

Fab1525 in complex with the C-terminal alpha-TSR domain of the P. falciparum circumsporozoite protein

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Plasmodium falciparum 3D7 (Taxon ID: 36329)
Streptococcus sp. group G (Taxon ID: 1320)

Expression System(s):

Cricetulus griseus, Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.20 Å

R-Value Free:

0.23

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

P 61 2 2

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Circumsporozoite protein
Gene (Uniprot):CSP
Chain IDs:C (auth: A)
Chain Length:73
Number of Molecules:1
Biological Source:Plasmodium falciparum 3D7

UniProt ID:Q7K740 Pfam ID:PF00090

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Immunoglobulin G-binding prot
Gene (Uniprot):spg
Chain IDs:D (auth: C)
Chain Length:56
Number of Molecules:1
Biological Source:Streptococcus sp. group G

UniProt ID:P19909

Polymer Type:polypeptide(L)
Molecule:Fab1525 heavy chain
Chain IDs:A (auth: H)
Chain Length:227
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Fab1525 light chain
Chain IDs:B (auth: L)
Chain Length:212
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules