ISDA: 9MRP

Deposition Date 2025-01-08

Release Date 2025-07-16

Last Version Date 2026-07-29

Entry Detail

PDB ID:

9MRP

Keywords:

ANTIBIOTIC

Title:

Crystal structures of a cyanobacterial DAP epimerase bound to L,L-aziDAP

Biological Source:

Source Organism(s):

Anabaena sp. YBS01 (Taxon ID: 2490939)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.50 Å

R-Value Free:

0.24

R-Value Work:

0.22

R-Value Observed:

0.23

Space Group:

P 1 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Diaminopimelate epimerase
Gene (Uniprot):dapF
Chain IDs:A, B, C, D
Chain Length:285
Number of Molecules:4
Biological Source:Anabaena sp. YBS01

UniProt ID:A0A5Q0GFR1 Pfam ID:PF01678 EC:5.1.1.7

Ligand Molecules

ZDP

Primary Citation

Structure and inhibition of diaminopimelic acid epimerase by slow-binding alpha-methyl amino acids.

Lamer, T, Chen, P, Catenza, K, Perov, I, L, B, Hsiao, Y.T, Van Oers, T.J, Lemieux, M.J, Vederas, J.C.Show

Protein Sci. 34 e70139 e70139 (2025)

PMID: 40299312 DOI: 10.1002/pro.70139

Primary Citation of related structures

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