9MKF image
Deposition Date 2024-12-17
Release Date 2026-04-15
Last Version Date 2026-04-15
Entry Detail
PDB ID:
9MKF
Keywords:
MEMBRANE PROTEIN
Title:
Rat TRPV2 bound to AV2-1 agonist
Biological Source:
Source Organism(s):
Rattus norvegicus (Taxon ID: 10116)
Expression System(s):
Saccharomyces cerevisiae
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.83 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9MKF validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Transient receptor potential
Gene (Uniprot):Trpv2
Chain IDs:A, B, C, D
Chain Length:761
Number of Molecules:4
Biological Source:Rattus norvegicus
UniProt ID:Q9WUD2 Pfam ID:PF12796, PF00520
Ligand Molecules
A1BMB
PEX
Primary Citation
Defining AV2-1 as a novel pharmacological probe to target human and rodent TRPV2.
Br. J. Pharmacol. ? ? ? (2026)
PMID: 41913383 DOI: 10.1111/bph.70413
Primary Citation of related structures
9MKF
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