ISDA: 9M9Z

Deposition Date 2025-03-13

Release Date 2026-03-18

Last Version Date 2026-09-30

Entry Detail

PDB ID:

9M9Z

Keywords:

MEMBRANE PROTEIN

Title:

Crystal structure of MctB from Mycobacterium tuberculosis at 2.3 Angstroms resolution

Biological Source:

Source Organism(s):

Mycobacterium tuberculosis CDC1551 (Taxon ID: 83331)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.31 Å

R-Value Free:

0.26

R-Value Work:

0.21

R-Value Observed:

0.22

Space Group:

P 4 2 2

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Copper transporter MctB
Gene (Uniprot):mctB
Chain IDs:A, B (auth: C)
Chain Length:297
Number of Molecules:2
Biological Source:Mycobacterium tuberculosis CDC1551

UniProt ID:P9WJ82 Pfam ID:PF11382

Ligand Molecules

GOL

IMD

Primary Citation

Oligomerization is required for channel formation of MctB and for copper resistance of Mycobacterium tuberculosis.

Siroy, A, Sun, D, Paul, A, Rowland, J.L, Jones, L.M, Prevelige, P, Tian, C, Niederweis, M.Show

J.Biol.Chem. 302 111037 111037 (2026)

PMID: 41380963 DOI: 10.1016/j.jbc.2025.111037

Primary Citation of related structures

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