ISDA: 9M8E

Deposition Date 2025-03-11

Release Date 2026-09-16

Last Version Date 2026-09-16

Entry Detail

PDB ID:

9M8E

Keywords:

OXIDOREDUCTASE

Title:

Cryo-EM structure of the dihydrolipoamide dehydrogenase complexed with the binding domain of the dihydrolipoyl transacetylase from Mycobacterium tuberculosis pyruvate dehydrogenase complex

Biological Source:

Source Organism(s):

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (Taxon ID: 83332)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.53 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Dihydrolipoyl dehydrogenase
Chain IDs:B, C (auth: A)
Chain Length:474
Number of Molecules:2
Biological Source:Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Polymer Type:polypeptide(L)
Molecule:Dihydrolipoyllysine-residue a
Chain IDs:A (auth: C)
Chain Length:563
Number of Molecules:1
Biological Source:Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Ligand Molecules

FAD

Primary Citation

Structure of Mycobacterium Central Carbon Metabolism Supercomplex

Wang, P, Mu, A, Wang, Q.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

Feedback Form