ISDA: 9M7I

Deposition Date 2025-03-10

Release Date 2026-03-18

Last Version Date 2026-03-18

Entry Detail

PDB ID:

9M7I

Keywords:

OXIDOREDUCTASE

Title:

Crystal structure of FtmoX1 complexes with tetrahydroisoquinoline

Biological Source:

Source Organism(s):

Aspergillus fumigatus (Taxon ID: 746128)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.75 Å

R-Value Free:

0.24

R-Value Work:

0.20

R-Value Observed:

0.21

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Verruculogen synthase
Gene (Uniprot):ftmOx1
Chain IDs:A, B
Chain Length:290
Number of Molecules:2
Biological Source:Aspergillus fumigatus

UniProt ID:B9WZX5

Ligand Molecules

A1EM0

AKG

Primary Citation

Versatile C(sp3)-H functionalization Catalyzed by Verruculogen Synthase (FtmOx1) Enables Rapid Late-stage Modification of Phenethylamines and Tetrahydroisoquinolines

Zhang, J.P, Liang, H.R.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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