9LYI image
Deposition Date 2025-02-20
Release Date 2026-04-15
Last Version Date 2026-04-15
Entry Detail
PDB ID:
9LYI
Keywords:
METAL BINDING PROTEIN
Title:
Cryo-EM structure of collagenase H (E416Q mutant) from Hathewaya histolytica in complex with collagen model peptide (Pro-Hyp-Gly)12
Biological Source:
Source Organism(s):
Hathewaya histolytica (Taxon ID: 1498)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.80 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9LYI validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Collagenase ColH
Gene (Uniprot):colH
Mutagens:E416Q
Chain IDs:A
Chain Length:983
Number of Molecules:1
Biological Source:Hathewaya histolytica
UniProt ID:Q46085 EC:3.4.24.3
Polymer Type:polypeptide(L)
Molecule:(Pro-Hyp-Gly)12
Chain IDs:B, C, D
Chain Length:36
Number of Molecules:3
Biological Source:Homo sapiens
Ligand Molecules
CA
ZN
Primary Citation
Bacterial collagenase harnesses collagen geometry for processive cleavage.
Nat Commun ? ? ? (2026)
PMID: 41927550 DOI: 10.1038/s41467-026-71099-3
Primary Citation of related structures
9LYI
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