9LRM image
Deposition Date 2025-01-31
Release Date 2026-04-15
Last Version Date 2026-04-15
Entry Detail
PDB ID:
9LRM
Keywords:
METAL BINDING PROTEIN
Title:
Cryo-EM structure of collagenase H (E416Q mutant) from Hathewaya histolytica in complex with collagen model peptide (Pro-Hyp-Gly)10
Biological Source:
Source Organism(s):
Hathewaya histolytica (Taxon ID: 1498)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.40 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9LRM validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Collagenase ColH
Gene (Uniprot):colH
Mutagens:E416Q
Chain IDs:A, E (auth: G)
Chain Length:983
Number of Molecules:2
Biological Source:Hathewaya histolytica
UniProt ID:Q46085 EC:3.4.24.3
Polymer Type:polypeptide(L)
Molecule:(Pro-Hyp-Gly)10
Chain IDs:B, C (auth: D), D (auth: C)
Chain Length:30
Number of Molecules:3
Biological Source:Homo sapiens
Ligand Molecules
CA
ZN
Primary Citation
Bacterial collagenase harnesses collagen geometry for processive cleavage.
Nat Commun ? ? ? (2026)
PMID: 41927550 DOI: 10.1038/s41467-026-71099-3
Primary Citation of related structures
9LRM
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