ISDA: 9LER

Deposition Date 2025-01-07

Release Date 2026-01-14

Last Version Date 2026-10-21

Entry Detail

PDB ID:

9LER

Keywords:

OXIDOREDUCTASE

Title:

Crystal Structure of FtmOx1 complexes with alkylamine derivative

Biological Source:

Source Organism(s):

Aspergillus fumigatus (Taxon ID: 746128)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.68 Å

R-Value Free:

0.23

R-Value Work:

0.19

R-Value Observed:

0.20

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Verruculogen synthase
Gene (Uniprot):ftmOx1
Chain IDs:A, B
Chain Length:291
Number of Molecules:2
Biological Source:Aspergillus fumigatus

UniProt ID:B9WZX5 EC:1.14.11.38

Ligand Molecules

A1EKG

AKG

Primary Citation

FtmOx1-catalyzed diverse C(sp3)-H oxyfunctionalization enables versatile late-stage diversification of phenethylamines and tetrahydroisoquinolines

Zhang, J, Liang, H, Shang, A, Wu, C, Yu, J, Zhang, G, Chen, Y, Wang, M.W, Tang, G.L, Sun, A, Zhou, S, Liu, H.Show

Nat Commun ? ? ? (2026)

DOI: 10.1038/s41467-026-78405-z

Primary Citation of related structures

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