ISDA: 9L9M

Deposition Date 2024-12-30

Release Date 2026-01-14

Last Version Date 2026-07-29

Entry Detail

PDB ID:

9L9M

Keywords:

TOXIN

Title:

Structure of Gh-TDH in Complex with 10-nt match Double-Stranded DNA

Biological Source:

Source Organism(s):

Grimontia hollisae (Taxon ID: 673)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli 'bl21-gold(de3)plyss ag'

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.42 Å

R-Value Free:

0.20

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

P 4 21 2

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Thermostable direct hemolysin
Gene (Uniprot):tdh3
Chain IDs:A
Chain Length:165
Number of Molecules:1
Biological Source:Grimontia hollisae

UniProt ID:A0A377HK12

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*CP*TP*CP*TP*AP*TP*
Chain IDs:B
Chain Length:10
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules

SO4

Primary Citation

Structural and biochemical characterization of Grimontia hollisae thermostable direct hemolysin with DNA reveals first Vibrio hemolysin with nuclease activity.

Hsiao, P.Y, Wang, Y.K, Huang, S.C, Chou, F.P, Huang, T.Y, Lin, Y.C, Kuo, Y.M, Wu, T.K, Chang, C.Y.Show

Nucleic Acids Res. 54 ? ? (2026)

PMID: 42406632 DOI: 10.1093/nar/gkag679

Primary Citation of related structures

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