ISDA: 9L90

Deposition Date 2024-12-28

Release Date 2025-10-22

Last Version Date 2025-10-22

Entry Detail

PDB ID:

9L90

Keywords:

MEMBRANE PROTEIN

Title:

The crystal structure of human RyR3 Repeat12 domain in complex with Dantrolene and AMP-PCP

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli 'bl21-gold(de3)plyss ag'

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.79 Å

R-Value Free:

0.31

R-Value Work:

0.27

Space Group:

P 21 21 21

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ryanodine receptor 3
Gene (Uniprot):RYR3
Chain IDs:A, B, C, D
Chain Length:218
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:Q15413 Pfam ID:PF02026

Ligand Molecules

ACP

U1C

Primary Citation

Structural Basis for the Modulation of Ryanodine Receptor by Dantrolene and Azumolene

Hadiatullah, H, Lin, L, Yuchi, Z.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

Feedback Form