ISDA: 9L8E

Deposition Date 2024-12-27

Release Date 2025-12-31

Last Version Date 2026-07-29

Entry Detail

PDB ID:

9L8E

Keywords:

TOXIN

Title:

Structure of Gh-TDH with Additional N-Terminus in Complex with Double-Stranded DNA Containing a 2-Nucleotide 5' Overhang

Biological Source:

Source Organism(s):

Grimontia hollisae (Taxon ID: 673)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.37 Å

R-Value Free:

0.19

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

P 4 21 2

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Hemolysin, heat labile
Chain IDs:A
Chain Length:165
Number of Molecules:1
Biological Source:Grimontia hollisae

UniProt ID:P14711 Pfam ID:PF03347

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*CP*TP*CP*AP*CP*TP*
Chain IDs:B
Chain Length:12
Number of Molecules:1
Biological Source:synthetic construct

Primary Citation

Structural and biochemical characterization of Grimontia hollisae thermostable direct hemolysin with DNA reveals first Vibrio hemolysin with nuclease activity.

Hsiao, P.Y, Wang, Y.K, Huang, S.C, Chou, F.P, Huang, T.Y, Lin, Y.C, Kuo, Y.M, Wu, T.K, Chang, C.Y.Show

Nucleic Acids Res. 54 ? ? (2026)

PMID: 42406632 DOI: 10.1093/nar/gkag679

Primary Citation of related structures

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