9K70 image
Deposition Date 2024-10-22
Release Date 2026-04-29
Last Version Date 2026-11-11
Entry Detail
PDB ID:
9K70
Keywords:
DNA-RNA HYBRID
Title:
A (3+1) hybrid G-quadruplex assembled between two strands of human telomeric DNA and RNA
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Method Details:
Experimental Method:
SOLUTION NMR
Conformers Calculated:
500
Conformers Submitted:
12
Selection Criteria:
structures with the lowest energy
9K70 validation report missing
Macromolecular Entities
Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*GP*GP*GP*TP*TP*AP*
Chain IDs:A
Chain Length:15
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(*UP*AP*GP*GP*GP*U)-
Chain IDs:B
Chain Length:6
Number of Molecules:1
Biological Source:Homo sapiens
Ligand Molecules
NA
Primary Citation
A Guanine Ribonucleotide Atypically Adaptive to the Syn Glycosidic Conformation in a Human Telomeric DNA-TERRA RNA Hybrid G-Quadruplex with (3 + 1) Mixed Strand Orientations Studied by NMR.
J.Am.Chem.Soc. 148 27189 27202 (2026)
PMID: 42358070 DOI: 10.1021/jacs.6c03261
Primary Citation of related structures
9K70
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