ISDA: 9K70

Deposition Date 2024-10-22

Release Date 2026-04-29

Last Version Date 2026-04-29

Entry Detail

PDB ID:

9K70

Keywords:

DNA-RNA HYBRID

Title:

A (3+1) hybrid G-quadruplex assembled between two strands of human telomeric DNA and RNA

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Method Details:

Experimental Method:

SOLUTION NMR

Conformers Calculated:

500

Conformers Submitted:

Selection Criteria:

structures with the lowest energy

Download Validation Report

Macromolecular Entities

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*GP*GP*GP*TP*TP*AP*
Chain IDs:A
Chain Length:15
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(*UP*AP*GP*GP*GP*U)-
Chain IDs:B
Chain Length:6
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

Primary Citation

Guanine ribonucleotide atypically adaptive to syn glycosidic conformation in an RNA-DNA hybrid G-quadruplex with topologically (3+1) mixed strand orientation

Fu, W.Q, Zhang, N.Show

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Primary Citation of related structures

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