9IBC image
Deposition Date 2025-02-12
Release Date 2026-08-26
Last Version Date 2026-08-26
Entry Detail
PDB ID:
9IBC
Keywords:
Title:
Kinetoplastid ATP-dependent RNA helicase PRP22/DHX8 in closed conformation bound to pre-mRNA
Biological Source:
Source Organism(s):
Method Details:
Experimental Method:
Resolution:
3.51 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Splicing factor Cactin C-term
Gene (Uniprot):LtaPh_2824100
Chain IDs:A (auth: LF)
Chain Length:706
Number of Molecules:1
Biological Source:Leishmania tarentolae
Polymer Type:polypeptide(L)
Molecule:RNA helicase
Gene (Uniprot):LtaPh_3629000
Chain IDs:B (auth: LV)
Chain Length:1087
Number of Molecules:1
Biological Source:Leishmania tarentolae
Polymer Type:polypeptide(L)
Molecule:NF-kappa-B-activating protein
Gene (Uniprot):LtaPh_3306200, LtaPh_9910501
Chain IDs:C (auth: LZ)
Chain Length:403
Number of Molecules:1
Biological Source:Leishmania tarentolae
Polymer Type:polyribonucleotide
Molecule:Pre-mRNA
Chain IDs:E (auth: RN)
Chain Length:7
Number of Molecules:1
Biological Source:Leishmania tarentolae
Polymer Type:polypeptide(L)
Molecule:Probable RNA helicase
Chain IDs:D (auth: TN)
Chain Length:1181
Number of Molecules:1
Biological Source:Leishmania tarentolae
Ligand Molecules
Primary Citation
Structural insights into Spliced Leader RNA trans-splicing in parasitic Trypanosomatids
To Be Published ? ? ? (?)
Primary Citation of related structures
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