9I3P image
Deposition Date 2025-01-23
Release Date 2026-04-29
Last Version Date 2026-04-29
Entry Detail
PDB ID:
9I3P
Keywords:
SIGNALING PROTEIN
Title:
CryoEM structure of the Themis:Grb2 complex with bound ProMacrobody 256
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)
Escherichia coli (Taxon ID: 562)
Expression System(s):
Homo sapiens, Escherichia coli
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.30 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9I3P validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Growth factor receptor-bound
Gene (Uniprot):GRB2
Chain IDs:A
Chain Length:224
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P62993
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Protein THEMIS
Chain IDs:B
Chain Length:563
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q8N1K5
Protein Blast
Polymer Type:polypeptide(L)
Molecule:ProMacrobody 256
Gene (Uniprot):malE
Chain IDs:C
Chain Length:478
Number of Molecules:1
Biological Source:synthetic construct, Escherichia coli
UniProt ID:9I3P,P0AEY0 EC:3.5.4.38
Ligand Molecules
NA
Peptide-like Molecules
PRD_900001
Primary Citation
Structure and mechanism of the constitutive Themis-Grb2 complex in T cell receptor signalling
To Be Published ? ? ? (?)
Primary Citation of related structures
9I3P
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