9HMW image
Deposition Date 2024-12-09
Release Date 2026-02-04
Last Version Date 2026-06-24
Entry Detail
PDB ID:
9HMW
Keywords:
RIBOSOME
Title:
Structure of the Arabidopsis thaliana 80S ribosome OVAC mutant in complex with P- and E-site tRNAs and mRNA
Biological Source:
Source Organism(s):
Arabidopsis thaliana (Taxon ID: 3702)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.25 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9HMW validation report missing
Macromolecular Entities
Polymer Type:polyribonucleotide
Molecule:Ribosomal RNA 5.8S
Chain IDs:A (auth: 3)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
Polymer Type:polyribonucleotide
Molecule:Ribosomal RNA 25S
Chain IDs:B (auth: A)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS3A
Chain IDs:AB (auth: AA)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9SIP7 Pfam ID:PF07650, PF00189
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS9C
Chain IDs:YA (auth: AB)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9FLF0 Pfam ID:PF00163, PF01479
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS2B, US5U, US5V
Chain IDs:X (auth: AC)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q93VB8 Pfam ID:PF00333, PF03719
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS5B
Chain IDs:CA (auth: AD)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P51427 Pfam ID:PF00177
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS15AA, RPS15AF
Chain IDs:L (auth: AE)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P42798 Pfam ID:PF00410
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS16A
Chain IDs:EB (auth: AF)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9SK22 Pfam ID:PF00380
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL13B
Chain IDs:BB (auth: AG)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P41127 Pfam ID:PF01294
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL14B
Chain IDs:Z (auth: AH)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9T043 Pfam ID:PF01929
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS10A
Chain IDs:AC (auth: AI)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9SW09 Pfam ID:PF03501
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL18C
Chain IDs:DA (auth: AJ)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q940B0 Pfam ID:PF17135
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL19A
Chain IDs:WA (auth: AK)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9SRX2 Pfam ID:PF01280, PF25476
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Ribosomal protein L18ae/LX fa
Gene (Uniprot):L18AB
Chain IDs:Q (auth: AL)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:A0A1P8AY36 Pfam ID:PF01775
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL21A, RPL21C
Chain IDs:W (auth: AM)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q43291 Pfam ID:PF01157
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL22B
Chain IDs:PB (auth: AN)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9M9W1 Pfam ID:PF01776
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL24A
Chain IDs:UA (auth: AO)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q42347 Pfam ID:PF01246
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL27C
Chain IDs:N (auth: AP)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P51419 Pfam ID:PF01777
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL28A
Chain IDs:KB (auth: AQ)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:O82204 Pfam ID:PF01778
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:60S ribosomal protein L29
Gene (Uniprot):T8E24.9
Chain IDs:H (auth: AR)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:F4JC32 Pfam ID:PF01779
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL30B
Chain IDs:IA (auth: AT)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q8VZ19 Pfam ID:PF01248
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL31B
Chain IDs:I (auth: AU)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9STR1 Pfam ID:PF01198
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL32A
Chain IDs:BA (auth: AV)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P49211 Pfam ID:PF01655
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL35AC
Chain IDs:T (auth: AW)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9C912 Pfam ID:PF01247
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL36B
Chain IDs:M (auth: AX)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9M352 Pfam ID:PF01158
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL37A
Chain IDs:UB (auth: AY)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q8LFH7 Pfam ID:PF01907
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL38A, RPL38B
Chain IDs:HB (auth: AZ)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:O22860 Pfam ID:PF01781
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS8A
Chain IDs:TB (auth: Aa)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q93VG5 Pfam ID:PF01201
Polymer Type:polyribonucleotide
Molecule:Messenger RNA (poly-U)
Chain IDs:XB (auth: B1)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL39A, RPL39C
Chain IDs:DB (auth: BA)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P51424 Pfam ID:PF00832
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS17D
Chain IDs:OB (auth: BB)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9LZ17 Pfam ID:PF00833
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPL41A, RPL41C, RPL41D, RPL41E, RPL41G
Chain IDs:E (auth: BC)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P62120 Pfam ID:PF05162
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL36AA, RPL36AB
Chain IDs:U (auth: BD)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:O23290 Pfam ID:PF00935
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL37AC
Chain IDs:IB (auth: BE)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q8RXU5 Pfam ID:PF01780
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL6B
Chain IDs:ZA (auth: BF)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9C9C6 Pfam ID:PF03868, PF01159
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL7AB
Chain IDs:MA (auth: BG)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9LZH9 Pfam ID:PF01248
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL13AB
Chain IDs:FA (auth: BH)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9LRX8 Pfam ID:PF00572
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL23A, RPL23B, RPL23C
Chain IDs:Y (auth: BI)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P49690 Pfam ID:PF00238
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL10B
Chain IDs:TA (auth: BJ)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q08770 Pfam ID:PF00252
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL5A
Chain IDs:HA (auth: BK)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q8LBI1 Pfam ID:PF17144, PF14204
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS19C
Chain IDs:RB (auth: BL)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9FNP8 Pfam ID:PF01090
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL17A
Chain IDs:F (auth: BM)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q93VI3 Pfam ID:PF00237
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL23AB
Chain IDs:LA (auth: BN)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9M3C3 Pfam ID:PF03939, PF00276
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL26A
Chain IDs:G (auth: BO)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P51414 Pfam ID:PF16906, PF00467
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL35C
Chain IDs:KA (auth: BP)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9M3D2 Pfam ID:PF00831
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL8A
Chain IDs:EA (auth: BQ)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P46286 Pfam ID:PF00181, PF03947
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Ribosomal protein L30/L7 fami
Gene (Uniprot):F6E13.25
Chain IDs:QA (auth: BR)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:F4IT48 Pfam ID:PF08079, PF00327
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):ARP1
Chain IDs:V (auth: BS)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P17094 Pfam ID:PF00297
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL4A
Chain IDs:AA (auth: BT)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9SF40 Pfam ID:PF00573, PF14374
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL11A
Chain IDs:PA (auth: BU)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P42795 Pfam ID:PF00281, PF00673
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS3AB
Chain IDs:SA (auth: BV)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q42262 Pfam ID:PF01015
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS21C
Chain IDs:VA (auth: BW)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q3E902 Pfam ID:PF01249
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS20B
Chain IDs:ZB (auth: Ba)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9STY6 Pfam ID:PF00338
Polymer Type:polyribonucleotide
Molecule:Ribosomal RNA 5S
Chain IDs:D (auth: C3)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS29A, RPS29B, RPS29C
Chain IDs:VB (auth: Ca)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q680P8 Pfam ID:PF00253
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS13B
Chain IDs:GA (auth: Da)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P59224 Pfam ID:PF08069, PF00312
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL15A
Chain IDs:P (auth: Ea)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:O23515 Pfam ID:PF00827
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL34A
Chain IDs:NA (auth: Fa)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q42351 Pfam ID:PF01199
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Ubiquitin-ribosomal protein e
Gene (Uniprot):RPL40A
Chain IDs:CB (auth: Ga)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:B9DHA6 Pfam ID:PF00240, PF01020
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL27AC
Chain IDs:OA (auth: Ha)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P49637 Pfam ID:PF00828
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):RPL9B, RPL9C
Chain IDs:K (auth: Ia)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P49209 Pfam ID:PF00347
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS4D
Chain IDs:O (auth: Ja)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q8VYK6 Pfam ID:PF08071, PF01479, PF00900, PF00467, PF16121
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS24B
Chain IDs:S (auth: Ka)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q8LC83 Pfam ID:PF01282
Polymer Type:polypeptide(L)
Molecule:Nascent polypeptide (poly-A)
Chain IDs:BC (auth: L3)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS25E
Chain IDs:SB (auth: La)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9T029 Pfam ID:PF03297
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS26A
Chain IDs:J (auth: Ma)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P49206 Pfam ID:PF01283
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS27B
Chain IDs:XA (auth: Na)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9M2F1 Pfam ID:PF01667
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS28C
Chain IDs:LB (auth: Oa)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P34789 Pfam ID:PF01200
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS30A, RPS30B, RPS30C
Chain IDs:JA (auth: Pa)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P49689 Pfam ID:PF04758
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS7C
Chain IDs:QB (auth: Ra)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q8LD03 Pfam ID:PF01251
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS6B
Chain IDs:GB (auth: Ta)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P51430 Pfam ID:PF01092
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS14B
Chain IDs:MB (auth: Ua)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9CAX6 Pfam ID:PF00411
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS23B
Chain IDs:R (auth: Va)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P49201 Pfam ID:PF00164
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS18A, RPS18B, RPS18C
Chain IDs:FB (auth: Wa)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P34788 Pfam ID:PF00416
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS11A
Chain IDs:RA (auth: Xa)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:P16181 Pfam ID:PF16205, PF00366
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS15C
Chain IDs:NB (auth: Ya)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q9FY65 Pfam ID:PF00203
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPSaA
Chain IDs:JB (auth: Za)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
UniProt ID:Q08682 Pfam ID:PF00318
Polymer Type:polyribonucleotide
Molecule:Ribosomal RNA 18S
Chain IDs:WB (auth: h1)
Chain Length:0
Number of Molecules:1
Biological Source:Arabidopsis thaliana
Polymer Type:polyribonucleotide
Molecule:Transfer RNA Phe (GAA)
Chain IDs:C (auth: i2), YB (auth: W2)
Chain Length:0
Number of Molecules:2
Biological Source:Arabidopsis thaliana
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
A2M A A modified residue
HIC V HIS modified residue
MLY CB LYS modified residue
OMG A G modified residue
PSU A U modified residue
Ligand Molecules
EPE
K
MG
SPD
TER
ZN
Primary Citation
Recruitment of bifunctional regulator thermospermine to methylated ribosomes directs xylem fate.
Science 391 694 699 (2026)
PMID: 41678627 DOI: 10.1126/science.adx2867

Abstact

Polyamines are often associated with ribosomes and are thought to stabilize their integrity. In Arabidopsis, the polyamine thermospermine (tSpm) affects xylem cell fate. tSpm induces translation of SUPPRESSOR-OF-ACAULIS51 (SAC51) and SAC51-LIKEs (SACLs), which inhibit heterodimerization of the xylem development proteins LONESOME-HIGHWAY (LHW) and TARGET-OF-MONOPTEROS5. Here, we report a methyltransferase, OVERACHIEVER, that methylates the peptidyl transferase center of the 25S ribosomal RNA (rRNA). Residue m(3)U2952 promotes functional tSpm binding to a specific site connecting the P-site transfer RNA (tRNA) with rRNA residues in the peptidyl transferase center. This interaction enhances the translation of SACLs but inhibits that of LHW. Our study uncovers the dependency between a conserved rRNA base methylation and a polyamine in orchestrating cell fate decisions, highlighting a role for the ribosome chemical landscape in translational regulation.

Legend

Protein

Chemical

Disease

Primary Citation of related structures
9HMW
Feedback Form
Name
Email
Institute
Feedback