ISDA: 9DZJ

Deposition Date 2024-10-16

Release Date 2026-01-21

Last Version Date 2026-01-21

Entry Detail

PDB ID:

9DZJ

Keywords:

MEMBRANE PROTEIN

Title:

Human GC-A bound to ANP and 2xREGN5308

Biological Source:

Source Organism(s):

Mus musculus (Taxon ID: 10090)
Homo sapiens (Taxon ID: 9606)

Expression System(s):

Spodoptera frugiperda, Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.70 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Atrial natriuretic peptide re
Gene (Uniprot):NPR1
Chain IDs:E (auth: A), F (auth: B)
Chain Length:1031
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P16066 Pfam ID:PF01094, PF07714, PF00211 EC:4.6.1.2

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Atrial natriuretic peptide
Gene (Uniprot):NPPA
Chain IDs:G (auth: C)
Chain Length:28
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P01160 Pfam ID:PF00212

Polymer Type:polypeptide(L)
Molecule:REGN5308 - Heavy chain
Chain IDs:A (auth: H), C (auth: G)
Chain Length:227
Number of Molecules:2
Biological Source:Mus musculus

Polymer Type:polypeptide(L)
Molecule:REGN5308 - Light chain
Chain IDs:B (auth: L), D (auth: K)
Chain Length:213
Number of Molecules:2
Biological Source:Mus musculus

Ligand Molecules

NAG

Primary Citation

human NPR1 bound to ANP and 2xRGN5308

Liu, S, Huang, X.-Y.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

Feedback Form