ISDA: 9BT8

Deposition Date 2024-05-14

Release Date 2024-11-13

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9BT8

Keywords:

SIGNALING PROTEIN

Title:

Structure of Src in complex with beta-arrestin 1 revealing SH3 binding sites

Biological Source:

Source Organism(s):

Gallus gallus (Taxon ID: 9031)
Bacteriophage sp. (Taxon ID: 38018)
Lama glama (Taxon ID: 9844)
Rattus norvegicus (Taxon ID: 10116)
Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli 'bl21-gold(de3)plyss ag', Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.34 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Nanobody 32
Chain IDs:D (auth: A)
Chain Length:124
Number of Molecules:1
Biological Source:Lama glama

UniProt ID:9BT8

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Beta-arrestin-1
Gene (Uniprot):Arrb1
Mutagens:C59V, P120C, C125S, C140L, C150V, C242V, C251V, C269S
Chain IDs:E (auth: B)
Chain Length:392
Number of Molecules:1
Biological Source:Rattus norvegicus

UniProt ID:P29066 Pfam ID:PF00339, PF02752

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proto-oncogene tyrosine-prote
Gene (Uniprot):SRC
Mutagens:R95C, C185S, C238S, C245S, C277S, C400S
Chain IDs:A (auth: C)
Chain Length:477
Number of Molecules:1
Biological Source:Gallus gallus

UniProt ID:P00523 Pfam ID:PF00018, PF00017, PF07714 EC:2.7.10.2

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Antibody fragment Fab30, heav
Chain IDs:B (auth: H)
Chain Length:237
Number of Molecules:1
Biological Source:Bacteriophage sp.

UniProt ID:9BT8

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Antibody fragment Fab30, ligh
Chain IDs:F (auth: L)
Chain Length:215
Number of Molecules:1
Biological Source:Bacteriophage sp.

UniProt ID:9BT8

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Vasopressin V2 receptor
Gene (Uniprot):AVPR2
Chain IDs:C (auth: V)
Chain Length:29
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P30518

Modified Residue