ISDA: 8ZK7

Deposition Date 2024-05-15

Release Date 2025-05-21

Last Version Date 2026-05-20

Entry Detail

PDB ID:

8ZK7

Keywords:

LYASE

Title:

Crystal structure of the Decarboxylase KDC4427 mutant E468L from Enterobacter sp. CGMCC 5087

Biological Source:

Source Organism(s):

Enterobacter sp. CGMCC 5087 (Taxon ID: 2183878)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.32 Å

R-Value Free:

0.24

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

P 21 21 2

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Indolepyruvate decarboxylase
Gene (Uniprot):ipdC
Mutagens:E468L
Chain IDs:A, B
Chain Length:566
Number of Molecules:2
Biological Source:Enterobacter sp. CGMCC 5087

UniProt ID:A0A2U3EYQ2 Pfam ID:PF02776, PF00205, PF02775

Ligand Molecules

TPP

Primary Citation

Mechanistic Insights into the Substrate Promiscuity of alpha-Ketoacid Decarboxylases for Enhanced Higher-Alcohol Biosynthesis

Dong, S, Liu, L, Yang, Y, Liao, W, Zhang, X, Ling, C, Han, Y, Wang, L, Zhang, H.Show

Acs Sustain Chem Eng ? ? ? (2026)

DOI: 10.1021/acssuschemeng.5c13943

Primary Citation of related structures

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