8TMC image
Deposition Date 2023-07-29
Release Date 2025-02-12
Last Version Date 2026-02-25
Entry Detail
PDB ID:
8TMC
Keywords:
MEMBRANE PROTEIN
Title:
Cryo-EM structure of CorA in complex with conformation-specific synthetic antibody C12 and 20 mM MgCl2, State MG20-2
Biological Source:
Source Organism(s):
Thermotoga maritima (Taxon ID: 2336)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli 'bl21-gold(de3)plyss ag', Escherichia coli bl21
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.30 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
8TMC validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cobalt/magnesium transport pr
Gene (Uniprot):corA
Chain IDs:A, B, C, D, E
Chain Length:373
Number of Molecules:5
Biological Source:Thermotoga maritima
UniProt ID:Q9WZ31 Pfam ID:PF01544 EC:7.2.2.14
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:sAB C12 Heavy Chain
Chain IDs:F (auth: H), H (auth: F)
Chain Length:240
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:8TMC
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:sAB C12 Light Chain
Chain IDs:G (auth: L), I (auth: G)
Chain Length:215
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:8TMC
Ligand Molecules
MG
Primary Citation
Conformational ensembles of the magnesium channel CorA reveal structural basis for channel gating.
Proc. Natl. Acad. Sci. U.S.A. 123 e2512532123 e2512532123 (2026)
PMID: 41701836 DOI: 10.1073/pnas.2512532123
Primary Citation of related structures
8TMC
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