ISDA: 8QZJ

Deposition Date 2023-10-27

Release Date 2024-06-19

Last Version Date 2024-06-19

Entry Detail

PDB ID:

8QZJ

Keywords:

TRANSFERASE

Title:

Crystal structure of PptT-ADP from Mycobacterium tuberculosis

Biological Source:

Source Organism(s):

Mycobacterium tuberculosis (Taxon ID: 1773)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.00 Å

R-Value Free:

0.26

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

P 2 21 21

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:4'-phosphopantetheinyl transf
Gene (Uniprot):pptT
Chain IDs:A, B, C, D
Chain Length:247
Number of Molecules:4
Biological Source:Mycobacterium tuberculosis

UniProt ID:O33336 Pfam ID:PF17837, PF01648 EC:2.7.8.7

Ligand Molecules

A3P

Primary Citation

Catalytic Cycle of Type II 4'-Phosphopantetheinyl Transferases

Gavalda, S, Faille, A, Fioccola, S, Nguyen, M.C, Carivenc, C, Rottier, K, Rufin, Y, Saitta, S, Czaplicki, G, Guilhot, C, Chalut, C, Brut, M, Mourey, L, Pedelacq, J.D.Show

Acs Catalysis 14 8561 8575 (2024)

DOI: 10.1021/acscatal.3c06249

Primary Citation of related structures

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