ISDA: 6GRZ

Deposition Date 2018-06-13

Release Date 2019-06-12

Last Version Date 2024-11-06

Entry Detail

PDB ID:

6GRZ

Keywords:

IMMUNE SYSTEM

Title:

Crystal structure of the light chain dimer mH6

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.10 Å

R-Value Free:

0.23

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

I 1 2 1

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:mH6
Chain IDs:A, B
Chain Length:216
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:6GRZ

Ligand Molecules

GOL

Primary Citation

Inherent Biophysical Properties Modulate the Toxicity of Soluble Amyloidogenic Light Chains

J. Mol. Biol. ? ? ? (2020)

DOI: 10.1016/j.jmb.2019.12.015

Primary Citation of related structures