ISDA: 6BWW

Deposition Date 2017-12-15

Release Date 2018-12-19

Last Version Date 2024-03-13

Entry Detail

PDB ID:

6BWW

Keywords:

OXIDOREDUCTASE

Title:

Crystal structure of an acetate and Cymal-5 bound cytochrome P450 2B4 F429H mutant

Biological Source:

Source Organism(s):

Oryctolagus cuniculus (Taxon ID: 9986)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.10 Å

R-Value Free:

0.20

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

P 31 2 1

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Cytochrome P450 2B4
Gene (Uniprot):CYP2B4
Mutagens:F429H
Chain IDs:A
Chain Length:472
Number of Molecules:1
Biological Source:Oryctolagus cuniculus

UniProt ID:P00178 Pfam ID:PF00067 EC:1.14.14.1

Ligand Molecules

ACT

CM5

GOL

HEM

Primary Citation

Structure of cytochrome P450 2B4 with an acetate ligand and an active site hydrogen bond network similar to oxyferrous P450cam.

Yang, Y, Bu, W, Im, S, Meagher, J, Stuckey, J, Waskell, L.Show

J. Inorg. Biochem. 185 17 25 (2018)

PMID: 29730233 DOI: 10.1016/j.jinorgbio.2018.04.015

Primary Citation of related structures

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