ISDA: 5XGI

Deposition Date 2017-04-13

Release Date 2018-04-25

Last Version Date 2024-03-27

Entry Detail

PDB ID:

5XGI

Keywords:

TRANSFERASE/INHIBITOR

Title:

Crystal structure of PI3K complex with an inhibitor

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.56 Å

R-Value Free:

0.29

R-Value Work:

0.23

R-Value Observed:

0.24

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Phosphatidylinositol 4,5-bisp
Gene (Uniprot):PIK3CA
Chain IDs:A
Chain Length:1052
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P42336 Pfam ID:PF02192, PF00794, PF00792, PF00613, PF00454 EC:2.7.1.137

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Phosphatidylinositol 3-kinase
Gene (Uniprot):PIK3R1
Chain IDs:B
Chain Length:277
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P27986 Pfam ID:PF00017, PF16454 EC:2.7.1.153

Ligand Molecules