5KPQ image
Deposition Date 2016-07-05
Release Date 2016-12-14
Last Version Date 2023-11-08
Entry Detail
PDB ID:
5KPQ
Title:
Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
2.55 Å
R-Value Free:
0.28
R-Value Work:
0.23
R-Value Observed:
0.23
Space Group:
P 21 21 21
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Poly [ADP-ribose] polymerase
Gene (Uniprot):PARP1
Mutagens:V762A
Chain IDs:A, B
Chain Length:350
Number of Molecules:2
Biological Source:Homo sapiens
Ligand Molecules
Primary Citation
Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor
To be published ? ? ? (?)
Primary Citation of related structures
Feedback Form
Name
Email
Institute
Feedback