4F60 image
Deposition Date 2012-05-14
Release Date 2013-01-23
Last Version Date 2023-09-13
Entry Detail
PDB ID:
4F60
Keywords:
Title:
Crystal structure of Rhodococcus rhodochrous haloalkane dehalogenase mutant (T148L, G171Q, A172V, C176F).
Biological Source:
Source Organism(s):
Expression System(s):
Method Details:
Experimental Method:
Resolution:
1.45 Å
R-Value Free:
0.17
R-Value Work:
0.15
R-Value Observed:
0.15
Space Group:
P 21 21 21
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Haloalkane dehalogenase
Gene (Uniprot):dhaA
Mutagens:T148L, G171Q, A172V, C176F
Chain IDs:A
Chain Length:299
Number of Molecules:1
Biological Source:Rhodococcus rhodochrous
Ligand Molecules
Primary Citation
Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel.
Angew. Chem. Int. Ed. Engl. 52 1959 1963 (2013)
PMID: 23303607 DOI: 10.1002/anie.201206708
Primary Citation of related structures
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