ISDA: 43YY

Deposition Date 2026-07-22

Release Date 2026-08-05

Last Version Date 2026-08-05

Entry Detail

PDB ID:

43YY

Keywords:

VIRAL PROTEIN/IMMUNE SYSTEM

Title:

Cryo-EM structure of N19 Fab : D0D-S1A

Biological Source:

Source Organism(s):

Porcine epidemic diarrhea virus (Taxon ID: 28295)
Sus scrofa (Taxon ID: 9823)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.30 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Spike glycoprotein
Gene (Uniprot):S
Chain IDs:A
Chain Length:487
Number of Molecules:1
Biological Source:Porcine epidemic diarrhea virus

UniProt ID:A0A7G4RNN0

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:N19 VH
Chain IDs:B (auth: H)
Chain Length:144
Number of Molecules:1
Biological Source:Sus scrofa

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:N19 VL
Chain IDs:C (auth: L)
Chain Length:129
Number of Molecules:1
Biological Source:Sus scrofa

Ligand Molecules

NAG

Primary Citation

Locking Spike Domain 0 Conformation Impairs Fusion and Neutralizes Porcine Epidemic Diarrhea Virus

Wang, S, Liu, J.B, Wang, J.J, Su, M.Z, Li, Z.M, Wang, Z.C, Ma, Y, Li, Y, Liu, B.H, Zou, J.H, Zhu, X.R, Habib, G, Cheng, Y.Q, Li, H.Y, Zhou, M, Li, M, Liu, Y.T, He, J, Xiao, S.B, Li, W.T, Chen, X.W, Zhou, H.B, Xiong, X.L.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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