37UO image
Deposition Date 2026-08-06
Release Date 2026-09-09
Last Version Date 2026-09-09
Entry Detail
PDB ID:
37UO
Keywords:
VIRAL PROTEIN/RNA
Title:
Gammacoronavirus dual dsRNA-bound IBV nsp15 (same trimer)
Biological Source:
Source Organism(s):
Infectious bronchitis virus (Taxon ID: 11120)
synthetic construct (Taxon ID: 32630)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.20 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
37UO validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Nonstructural protein 15
Gene (Uniprot):1b
Mutagens:H225A
Chain IDs:A, B (auth: C), C (auth: D), D (auth: E), E (auth: F), H (auth: B)
Chain Length:339
Number of Molecules:6
Biological Source:Infectious bronchitis virus
UniProt ID:G4XMQ6
Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(*GP*UP*AP*GP*AP*UP*
Chain IDs:F (auth: G), I
Chain Length:20
Number of Molecules:2
Biological Source:synthetic construct
Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(P*AP*AP*AP*AP*UP*CP
Chain IDs:G (auth: H), J
Chain Length:22
Number of Molecules:2
Biological Source:synthetic construct
Ligand Molecules
NA
Primary Citation
Structural and biochemical analysis of the IBV nsp15 endoribonuclease reveals the necessity of peripheral site residues for activity
Biorxiv ? ? ? (2026)
DOI: 10.64898/2026.08.28.747898
Primary Citation of related structures
37UO
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