ISDA: 37EU

Deposition Date 2026-07-17

Release Date 2026-07-29

Last Version Date 2026-07-29

Entry Detail

PDB ID:

37EU

Keywords:

TRANSFERASE

Title:

Crystal Structure of Histone-lysine N-methyltransferase from Leishmania major in complex with S-ADENOSYL-L-HOMOCYSTEINE (P21 form)

Biological Source:

Source Organism(s):

Leishmania major strain Friedlin (Taxon ID: 347515)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.10 Å

R-Value Free:

0.26

R-Value Work:

0.24

R-Value Observed:

0.24

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone-lysine N-methyltransf
Gene (Uniprot):LMJF_07_0025
Chain IDs:A, B, C, D
Chain Length:258
Number of Molecules:4
Biological Source:Leishmania major strain Friedlin

UniProt ID:Q4QIU2 Pfam ID:PF08123

Ligand Molecules

BTB

GOL

SAH

Primary Citation

Crystal Structure of Histone-lysine N-methyltransferase from Leishmania major in complex with S-ADENOSYL-L-HOMOCYSTEINE (P21 form)

Liu, L, Lovell, S, Battaile, K.P.Show

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Primary Citation of related structures

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