ISDA: 36PK

Deposition Date 2026-06-24

Release Date 2026-09-16

Last Version Date 2026-09-16

Entry Detail

PDB ID:

36PK

Keywords:

RNA BINDING PROTEIN/RNA/DNA

Title:

VIPR Ternary Complex with a duplex dsDNA substrate, 10 subunits

Biological Source:

Source Organism(s):

Suspvirus SUSP1 (Taxon ID: 1985290)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.30 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polyribonucleotide
Molecule:SUSP1 viprRNA
Chain IDs:A
Chain Length:94
Number of Molecules:1
Biological Source:Suspvirus SUSP1

Polymer Type:polydeoxyribonucleotide
Molecule:Target DNA strand
Chain IDs:B
Chain Length:63
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:Non-target strand
Chain IDs:C
Chain Length:63
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polypeptide(L)
Molecule:SUSP1 Vipr protein
Chain IDs:D, E, F, G, H, I, J, K, L, M
Chain Length:202
Number of Molecules:10
Biological Source:Suspvirus SUSP1

Ligand Molecules

Primary Citation

VIPR RNA-guided DNA recognition by noncontiguous geometric triplex formation

Yoon, P.H, Docter, T.A, Zhang, Z.T, Loi, K, Lopez, S.C, Valentin-Alvarado, L.E, Tuck, O, Brohawn, S.G, Doudna, J.A.Show

Science ? ? ? (2026)

DOI: 10.1126/science.aei3472

Primary Citation of related structures

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