ISDA: 36JB

Deposition Date 2026-06-13

Release Date 2026-09-16

Last Version Date 2026-09-16

Entry Detail

PDB ID:

36JB

Keywords:

MEMBRANE PROTEIN

Title:

Coagulation factor V DTQQ, membrane-bound, on Ptd-choline : Ptd-serine 75:25 vesicles

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Mesocricetus auratus

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.90 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Coagulation factor V
Gene (Uniprot):F5
Mutagens:R709Q; del811-1491; R1545Q
Chain IDs:A
Chain Length:1515
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P12259 Pfam ID:PF07732, PF00754

Ligand Molecules

CU1

NAG

SEP

Primary Citation

Structural basis for membrane binding by coagulation factors V and VIII and their specificity for phosphatidylserine-containing membranes.

Kolyadko, V.N, Pumroy, R.A, Moiseenkova-Bell, V.Y, Krishnaswamy, S.Show

Proc.Natl.Acad.Sci.USA 123 e2622255123 e2622255123 (2026)

PMID: 42685075 DOI: 10.1073/pnas.2622255123

Primary Citation of related structures

Feedback Form