ISDA: 31ML

Deposition Date 2026-06-12

Release Date 2026-09-30

Last Version Date 2026-09-30

Entry Detail

PDB ID:

31ML

Keywords:

SUGAR BINDING PROTEIN

Title:

Crystal structure of the complex of galectin-8N-Methyl 2,6-anhydro-3-deoxy-3-S-(b-D-galactopyranosyl)-3-thio-D-glycero-L-altro-heptonate

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.50 Å

R-Value Free:

0.22

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

P 21 21 21

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Galectin-8
Gene (Uniprot):LGALS8
Chain IDs:A, B
Chain Length:317
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:O00214 Pfam ID:PF00337

Primary Citation

Structural and Biophysical Characterization of C-Glycosylic 1,2-Thiodisaccharides Reveals Determinants of Selective Binding to Galectin-7 and Galectin-8N.

Tsagkarakou, A.S, Kantsadi, A.L, Theodoridou, V.I, Veliotis, N, Lazar, L, Jozsef, J, Juhasz, L, Kontopidis, G, Leffler, H, Nilsson, U.J, Somsak, L, Leonidas, D.D.Show

Chemmedchem 21 e70439 e70439 (2026)

PMID: 42603778 DOI: 10.1002/cmdc.70439

Primary Citation of related structures

Feedback Form