ISDA: 31LN

Deposition Date 2026-06-11

Release Date 2026-09-09

Last Version Date 2026-09-09

Entry Detail

PDB ID:

31LN

Keywords:

SUGAR BINDING PROTEIN

Title:

Galectin-7 in complex with Methyl 2,6-anhydro-3-deoxy-3-S-(b-D-galactopyranosyl)-3-thio-D-glycero-L-altro-heptonate

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli 'bl21-gold(de3)plyss ag'

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.76 Å

R-Value Free:

0.21

R-Value Work:

0.16

R-Value Observed:

0.17

Space Group:

P 41 21 2

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Galectin-7
Gene (Uniprot):LGALS7, LGALS7B
Chain IDs:A, B
Chain Length:136
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P47929 Pfam ID:PF00337

Ligand Molecules

GOL

Primary Citation

Structural and Biophysical Characterization of C-Glycosylic 1,2-Thiodisaccharides Reveals Determinants of Selective Binding to Galectin-7 and Galectin-8N.

Tsagkarakou, A.S, Kantsadi, A.L, Theodoridou, V.I, Veliotis, N, Lazar, L, Jozsef, J, Juhasz, L, Kontopidis, G, Leffler, H, Nilsson, U.J, Somsak, L, Leonidas, D.D.Show

Chemmedchem 21 e70439 e70439 (2026)

PMID: 42603778 DOI: 10.1002/cmdc.70439

Primary Citation of related structures

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