31BG image
Deposition Date 2026-05-22
Release Date 2026-08-19
Last Version Date 2026-08-19
Entry Detail
PDB ID:
31BG
Keywords:
MEMBRANE PROTEIN
Title:
Cryo-EM structure of Dopamine 3 receptor:Go complex bound to bitopic AB13-46A
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Rattus norvegicus (Taxon ID: 10116)
Aequorea victoria (Taxon ID: 6100)
Expression System(s):
Trichoplusia ni
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.47 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
31BG validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Mutagens:S47N, G204A, E246A, M249K, A326S, K54E
Chain IDs:A
Chain Length:354
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Chain IDs:B
Chain Length:355
Number of Molecules:1
Biological Source:Rattus norvegicus
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Chain IDs:C
Chain Length:71
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Green fluorescent protein,D(3
Chain IDs:D (auth: R)
Chain Length:669
Number of Molecules:1
Biological Source:Aequorea victoria, Homo sapiens
Ligand Molecules
A1J83
Primary Citation
A Ligand-Triggered Receptor Conformation Enables the Design of Selective Agonists for the Dopamine 3 Receptor (D 3 R) Using a Bitopic Strategy.
Jacs Au 6 4138 4152 (2026)
PMID: 42529391 DOI: 10.1021/jacsau.6c00654
Primary Citation of related structures
31BG
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