ISDA: 30TO

Deposition Date 2026-05-13

Release Date 2026-08-26

Last Version Date 2026-08-26

Entry Detail

PDB ID:

30TO

Keywords:

PEPTIDE BINDING PROTEIN

Title:

14-3-3sigma protein binding to TSC2-strong peptide (RSH mutation) and stabilizer 3'deAc FC-A.

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.80 Å

R-Value Free:

0.20

R-Value Work:

0.17

Space Group:

C 2 2 21

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:14-3-3 protein sigma
Chain IDs:A
Chain Length:236
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:TSC2 peptide pS1254 wt
Chain IDs:B
Chain Length:10
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules