ISDA: 30AR

Deposition Date 2026-04-17

Release Date 2026-11-11

Last Version Date 2026-11-11

Entry Detail

PDB ID:

30AR

Keywords:

DNA BINDING PROTEIN

Title:

Cryo-EM structure of human PRIMPOL bound to the CMG helicase

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Trichoplusia ni, Escherichia coli bl21(de3)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.30 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Gene (Uniprot):MCM2
Chain IDs:A (auth: 2)
Chain Length:904
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P49736 EC:3.6.4.12

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Gene (Uniprot):MCM3
Chain IDs:B (auth: 3)
Chain Length:808
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P25205 EC:3.6.4.12

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Gene (Uniprot):MCM4
Chain IDs:C (auth: 4)
Chain Length:863
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P33991 EC:3.6.4.12

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Gene (Uniprot):MCM5
Chain IDs:D (auth: 5)
Chain Length:734
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P33992 EC:3.6.4.12

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Gene (Uniprot):MCM6
Chain IDs:E (auth: 6)
Chain Length:821
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q14566 EC:3.6.4.12

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Gene (Uniprot):MCM7
Chain IDs:F (auth: 7)
Chain Length:719
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P33993 EC:3.6.4.12

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Cell division control protein
Gene (Uniprot):CDC45
Chain IDs:G (auth: C)
Chain Length:566
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O75419

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA replication complex GINS
Gene (Uniprot):GINS4
Chain IDs:H (auth: G)
Chain Length:223
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q9BRT9

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA replication complex GINS
Gene (Uniprot):GINS1
Chain IDs:I
Chain Length:196
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q14691

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA replication complex GINS
Gene (Uniprot):GINS2
Chain IDs:J (auth: N)
Chain Length:185
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q9Y248

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed primase/polymera
Gene (Uniprot):PRIMPOL
Chain IDs:K (auth: P)
Chain Length:560
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q96LW4 EC:2.7.7.102

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA replication complex GINS
Gene (Uniprot):GINS3
Chain IDs:L (auth: S)
Chain Length:216
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q9BRX5

Ligand Molecules