ISDA: 2NPT

Deposition Date 2006-10-30

Release Date 2006-11-28

Last Version Date 2023-08-30

Entry Detail

PDB ID:

2NPT

Keywords:

TRANSFERASE

Title:

Crystal Structure of the complex of human mitogen activated protein kinase kinase 5 phox domain (MAP2K5-phox) with human mitogen activated protein kinase kinase kinase 2 phox domain (MAP3K2-phox)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.75 Å

R-Value Free:

0.24

R-Value Work:

0.19

R-Value Observed:

0.20

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Dual specificity mitogen-acti
Gene (Uniprot):MAP2K5
Chain IDs:A, C
Chain Length:106
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q13163 Pfam ID:PF00564 EC:2.7.12.2

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Mitogen-activated protein kin
Gene (Uniprot):MAP3K2
Chain IDs:B, D
Chain Length:100
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q9Y2U5 Pfam ID:PF00564 EC:2.7.12.2

Primary Citation

Crystal Structure of the complex of human mitogen activated protein kinase kinase 5 phox domain (MAP2K5-phox) with human mitogen activated protein kinase kinase kinase 2 phox domain (MAP3K2-phox)

Filippakopoulos, P, Debreczeni, J, Papagrigoriou, V, Turnbull, A, Edwards, A, Arrowsmith, C, Sundstrom, M, von Delft, F, Knapp, S.Show

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Primary Citation of related structures

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