ISDA: 29QG

Deposition Date 2026-03-30

Release Date 2026-09-23

Last Version Date 2026-09-23

Entry Detail

PDB ID:

29QG

Keywords:

VIRAL PROTEIN

Title:

Crystal structure of Parechovirus A1 RdRP in complex with GTP

Biological Source:

Source Organism(s):

Parechovirus ahumpari (Taxon ID: 3431395)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.86 Å

R-Value Free:

0.20

R-Value Work:

0.16

R-Value Observed:

0.16

Space Group:

C 1 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Genome polyprotein
Chain IDs:A
Chain Length:0
Number of Molecules:1
Biological Source:Parechovirus ahumpari

UniProt ID:Q66578

Ligand Molecules

GTP

Primary Citation

Crystal structures of Parechovirus A1 3D pol reveal a mechanism of conformational stabilization in +ssRNA virus RNA-dependent RNA polymerase.

Guryanov, S.G, Mitchell, C, Kajander, T, Butcher, S.J.Show

J.Struct.Biol. 218 108370 108370 (2026)

PMID: 42722143 DOI: 10.1016/j.jsb.2026.108370

Primary Citation of related structures

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