29HO image
Deposition Date 2026-03-12
Release Date 2026-09-09
Last Version Date 2026-09-09
Entry Detail
PDB ID:
29HO
Keywords:
Title:
Ternary complex of VCB, Baz2B-BD with compound 8
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
2.45 Å
R-Value Free:
0.27
R-Value Work:
0.23
Space Group:
P 21 21 21
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Elongin-B
Gene (Uniprot):ELOB
Chain IDs:A (auth: B)
Chain Length:104
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Elongin-C
Gene (Uniprot):ELOC
Chain IDs:B (auth: C)
Chain Length:97
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Bromodomain adjacent to zinc
Gene (Uniprot):BAZ2B
Chain IDs:C (auth: D)
Chain Length:117
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Isoform 1 of von Hippel-Linda
Gene (Uniprot):VHL
Chain IDs:D (auth: V)
Chain Length:162
Number of Molecules:1
Biological Source:Homo sapiens
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
CAS A CYS modified residue
Primary Citation
Chemical tools for BAZ2A/B biology: discovery of dual and BAZ2B-selective PROTAC degraders.
Rsc Med Chem ? ? ? (2026)
PMID: 42626597 DOI: 10.1039/d6md00244g
Primary Citation of related structures
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