ISDA: 28ZX

Deposition Date 2026-03-03

Release Date 2026-06-10

Last Version Date 2026-08-26

Entry Detail

PDB ID:

28ZX

Keywords:

RIBOSOME

Title:

human 48S PIC with mRNA (Kozak_1)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Homo (Taxon ID: 9605)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.80 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Eukaryotic translation initia
Gene (Uniprot):EIF3F
Chain IDs:TA (auth: 3f)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O00303 Pfam ID:PF01398, PF13012 EC:3.4.19.12

Polymer Type:polyribonucleotide
Molecule:mRNA_Kozak
Chain IDs:U (auth: B)
Chain Length:0
Number of Molecules:1
Biological Source:Homo

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Eukaryotic translation initia
Gene (Uniprot):EIF2S1
Chain IDs:KA (auth: D)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P05198 Pfam ID:PF00575, PF07541 EC:3.6.5.3

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Eukaryotic translation initia
Gene (Uniprot):EIF2S3
Chain IDs:LA (auth: E)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P41091 Pfam ID:PF00009, PF03144, PF09173 EC:3.6.5.3

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Eukaryotic translation initia
Gene (Uniprot):EIF2S2
Chain IDs:MA (auth: F)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P20042 Pfam ID:PF01873 EC:3.6.5.3

Polymer Type:polyribonucleotide
Molecule:initiator tRNA
Chain IDs:NA (auth: G)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Eukaryotic translation initia
Gene (Uniprot):EIF1AX
Chain IDs:OA (auth: H)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P47813 Pfam ID:PF01176

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:60S ribosomal protein L41
Gene (Uniprot):RPL41
Chain IDs:B (auth: Ln)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62945 Pfam ID:PF05162

Polymer Type:polyribonucleotide
Molecule:18S rRNA
Chain IDs:A (auth: S2)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein SA
Gene (Uniprot):RPSA
Chain IDs:D (auth: SA)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P08865 Pfam ID:PF00318, PF16122

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S3a
Gene (Uniprot):RPS3A
Chain IDs:E (auth: SB)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P61247 Pfam ID:PF01015

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S2
Gene (Uniprot):RPS2
Chain IDs:L (auth: SC)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P15880 Pfam ID:PF00333, PF03719

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S3
Gene (Uniprot):RPS3
Chain IDs:V (auth: SD)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P23396 Pfam ID:PF07650, PF00189 EC:4.2.99.18

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS4X
Chain IDs:C (auth: SE)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62701 Pfam ID:PF08071, PF00900, PF00467, PF16121

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S5
Gene (Uniprot):RPS5
Chain IDs:W (auth: SF)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P46782 Pfam ID:PF00177

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S6
Gene (Uniprot):RPS6
Chain IDs:M (auth: SG)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62753 Pfam ID:PF01092

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S7
Gene (Uniprot):RPS7
Chain IDs:F (auth: SH)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62081 Pfam ID:PF01251

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S8
Gene (Uniprot):RPS8
Chain IDs:G (auth: SI)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62241 Pfam ID:PF01201

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S9
Gene (Uniprot):RPS9
Chain IDs:N (auth: SJ)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P46781 Pfam ID:PF00163, PF01479

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S10
Gene (Uniprot):RPS10
Chain IDs:CA (auth: SK)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P46783 Pfam ID:PF03501

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS11
Chain IDs:H (auth: SL)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62280 Pfam ID:PF16205, PF00366

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S12
Gene (Uniprot):RPS12
Chain IDs:DA (auth: SM)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P25398 Pfam ID:PF01248

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S13
Gene (Uniprot):RPS13
Chain IDs:O (auth: SN)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62277 Pfam ID:PF08069, PF00312

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S14
Gene (Uniprot):RPS14
Chain IDs:P (auth: SO)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62263 Pfam ID:PF00411

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S15
Gene (Uniprot):RPS15
Chain IDs:IA (auth: SP)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62841 Pfam ID:PF00203

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S16
Gene (Uniprot):RPS16
Chain IDs:FA (auth: SQ)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62249 Pfam ID:PF00380

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S17
Gene (Uniprot):RPS17
Chain IDs:Y (auth: SR)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P08708 Pfam ID:PF00833

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S18
Gene (Uniprot):RPS18
Chain IDs:GA (auth: SS)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62269 Pfam ID:PF00416

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS19
Chain IDs:HA (auth: ST)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P39019 Pfam ID:PF01090

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S20
Gene (Uniprot):RPS20
Chain IDs:EA (auth: SU)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P60866 Pfam ID:PF00338

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S21
Gene (Uniprot):RPS21
Chain IDs:I (auth: SV)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P63220 Pfam ID:PF01249

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S15a
Gene (Uniprot):RPS15A
Chain IDs:Q (auth: SW)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62244 Pfam ID:PF00410

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S23
Gene (Uniprot):RPS23
Chain IDs:J (auth: SX)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62266 Pfam ID:PF00164

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S24
Gene (Uniprot):RPS24
Chain IDs:R (auth: SY)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62847 Pfam ID:PF01282

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):RPS25
Chain IDs:JA (auth: SZ)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62851 Pfam ID:PF03297

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S26
Gene (Uniprot):RPS26
Chain IDs:K (auth: Sa)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62854 Pfam ID:PF01283

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S27
Gene (Uniprot):RPS27
Chain IDs:S (auth: Sb)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P42677 Pfam ID:PF01667

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S28
Gene (Uniprot):RPS28
Chain IDs:BA (auth: Sc)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62857 Pfam ID:PF01200

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:40S ribosomal protein S29
Gene (Uniprot):RPS29
Chain IDs:Z (auth: Sd)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62273 Pfam ID:PF00253

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ubiquitin-like FUBI-ribosomal
Gene (Uniprot):FAU
Chain IDs:T (auth: Se)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62861 Pfam ID:PF00240, PF04758

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ubiquitin
Gene (Uniprot):RPS27A
Chain IDs:X (auth: Sf)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62979 Pfam ID:PF00240, PF01599

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Receptor of activated protein
Gene (Uniprot):RACK1
Chain IDs:AA (auth: Sg)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P63244 Pfam ID:PF00400

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Eukaryotic translation initia
Gene (Uniprot):EIF3A
Chain IDs:SA (auth: a)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q14152 Pfam ID:PF22591, PF01399

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Eukaryotic translation initia
Gene (Uniprot):EIF3C
Chain IDs:RA (auth: c)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q99613 Pfam ID:PF05470, PF01399, PF26569

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Eukaryotic translation initia
Gene (Uniprot):EIF3D
Chain IDs:QA (auth: d)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O15371 Pfam ID:PF05091

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Eukaryotic translation initia
Gene (Uniprot):EIF3E
Chain IDs:PA (auth: e)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P60228 Pfam ID:PF09440, PF01399, PF21357

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Eukaryotic translation initia
Gene (Uniprot):EIF3H
Chain IDs:VA (auth: h)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O15372 Pfam ID:PF01398, PF19445

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Eukaryotic translation initia
Gene (Uniprot):EIF3K
Chain IDs:WA (auth: k)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q9UBQ5 Pfam ID:PF10075

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Eukaryotic translation initia
Gene (Uniprot):EIF3L
Chain IDs:XA (auth: l)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q9Y262 Pfam ID:PF10255

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Eukaryotic translation initia
Gene (Uniprot):EIF3M
Chain IDs:UA (auth: m)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q7L2H7 Pfam ID:PF01399, PF18005

Modified Residue