28VY image
Deposition Date 2026-02-23
Release Date 2026-05-13
Last Version Date 2026-05-13
Entry Detail
PDB ID:
28VY
Keywords:
REPLICATION
Title:
sCMGE assembled on ARS1 DNA with Sld2 and RPA
Biological Source:
Source Organism(s):
Saccharomyces cerevisiae (Taxon ID: 4932)
synthetic construct (Taxon ID: 32630)
Expression System(s):
Saccharomyces cerevisiae, Escherichia coli
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.70 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
28VY validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Gene (Uniprot):MCM2
Chain IDs:A (auth: 2)
Chain Length:868
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P29469 Pfam ID:PF12619, PF14551, PF17207, PF00493, PF17855
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Gene (Uniprot):MCM3
Chain IDs:B (auth: 3)
Chain Length:1006
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P24279 Pfam ID:PF14551, PF17207, PF00493, PF17855, PF22207, PF23191
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Gene (Uniprot):MCM4
Chain IDs:C (auth: 4)
Chain Length:933
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P30665 Pfam ID:PF14551, PF17207, PF00493, PF17855, PF21128
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Minichromosome maintenance pr
Gene (Uniprot):MCM5
Chain IDs:D (auth: 5)
Chain Length:775
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P29496 Pfam ID:PF14551, PF17207, PF00493, PF17855, PF21933
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Gene (Uniprot):MCM6
Chain IDs:E (auth: 6)
Chain Length:1017
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P53091 Pfam ID:PF14551, PF17207, PF00493, PF17855, PF18263
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Gene (Uniprot):MCM7
Chain IDs:F (auth: 7)
Chain Length:845
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P38132 Pfam ID:PF14551, PF17207, PF00493, PF17855, PF24901
Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(P*GP*AP*TP*CP*GP*AP
Chain IDs:G (auth: A), H (auth: B)
Chain Length:27
Number of Molecules:2
Biological Source:synthetic construct
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA replication complex GINS
Gene (Uniprot):PSF3
Chain IDs:I (auth: C)
Chain Length:217
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:Q12146 Pfam ID:PF22466, PF05916
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA replication complex GINS
Gene (Uniprot):SLD5
Chain IDs:J (auth: D)
Chain Length:294
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:Q03406 Pfam ID:PF05916, PF16922
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cell division control protein
Gene (Uniprot):CDC45
Chain IDs:K (auth: E)
Chain Length:657
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:Q08032 Pfam ID:PF02724
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA polymerase epsilon subuni
Gene (Uniprot):DPB2
Chain IDs:L (auth: F)
Chain Length:689
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P24482 Pfam ID:PF04042
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA polymerase epsilon cataly
Gene (Uniprot):POL2
Chain IDs:M (auth: G)
Chain Length:2222
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P21951 Pfam ID:PF03104, PF22634, PF08490, PF23250, PF22912
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA replication complex GINS
Gene (Uniprot):PSF1
Chain IDs:N (auth: H)
Chain Length:208
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:Q12488 Pfam ID:PF05916, PF24997
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA replication complex GINS
Gene (Uniprot):PSF2
Chain IDs:O (auth: I)
Chain Length:213
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P40359 Pfam ID:PF25005, PF05916
Ligand Molecules
ADP
ATP
MG
ZN
Primary Citation
Structure of the pre-initiation complex explains CMG biogenesis
To Be Published ? ? ? (?)
Primary Citation of related structures
28VY
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