ISDA: 25TX

Deposition Date 2026-04-17

Release Date 2026-09-09

Last Version Date 2026-09-09

Entry Detail

PDB ID:

25TX

Keywords:

MEMBRANE PROTEIN

Title:

Cryo-EM structure of the 2:2 mGlu7-ELFN1 complex in conformation C

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

4.00 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Metabotropic glutamate recept
Gene (Uniprot):GRM7
Chain IDs:A, B
Chain Length:920
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q14831 Pfam ID:PF01094, PF07562, PF00003

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Protein ELFN1
Gene (Uniprot):ELFN1
Chain IDs:C, D
Chain Length:411
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P0C7U0 Pfam ID:PF13855, PF22986

Ligand Molecules

NAG

Primary Citation

Structural basis for the synaptic adhesion protein ELFN1-mediated modulation of mGlu7

Lin, S, Feng, Y, Shui, S, Chen, M, Chu, X, Yi, C, Han, S, Zhao, Q, Wu, B.Show

To be published ? ? ? (?)

Primary Citation of related structures

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