25CI image
Deposition Date 2026-03-29
Release Date 2026-11-11
Last Version Date 2026-11-11
Entry Detail
PDB ID:
25CI
Keywords:
METAL TRANSPORT
Title:
Structure of hTRPC3 T561A mutant with C2 symmetry
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.16 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
25CI validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Short transient receptor pote
Gene (Uniprot):TRPC3
Chain IDs:A (auth: C), B (auth: D), C (auth: A), D (auth: B)
Chain Length:866
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:Q13507
Ligand Molecules
A1L5I
CA
ZN
Primary Citation
Structural mechanism of TRPC3 channel activation by the moonwalker mutation.
Cell Discov 12 ? ? (2026)
PMID: 42957638 DOI: 10.1038/s41421-026-00936-y
Primary Citation of related structures
25CI
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