ISDA: 25CH

Deposition Date 2026-03-29

Release Date 2026-11-11

Last Version Date 2026-11-11

Entry Detail

PDB ID:

25CH

Keywords:

METAL TRANSPORT

Title:

Structure of hTRPC3 T561A mutant in the partially open state with C4 symmetry

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.93 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Short transient receptor pote
Gene (Uniprot):TRPC3
Chain IDs:A, B, C, D
Chain Length:866
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:Q13507

Ligand Molecules

A1L5I

Primary Citation

Structural mechanism of TRPC3 channel activation by the moonwalker mutation.

Zang, J, Tan, Y, Chen, Y, Guo, W, Zhao, X, Peng, H, Chen, L.Show

Cell Discov 12 ? ? (2026)

PMID: 42957638 DOI: 10.1038/s41421-026-00936-y

Primary Citation of related structures

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