25CG image
Deposition Date 2026-03-29
Release Date 2026-11-11
Last Version Date 2026-11-11
Entry Detail
PDB ID:
25CG
Keywords:
METAL TRANSPORT
Title:
Structure of hTRPC3 E603A/V637A/K607A mutant
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.78 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
25CG validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Short transient receptor pote
Gene (Uniprot):TRPC3
Mutagens:E603A,V637A,K607A
Chain IDs:A (auth: B), B (auth: A), C, D
Chain Length:836
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:Q13507
Ligand Molecules
CA
ZN
Primary Citation
Structural mechanism of TRPC3 channel activation by the moonwalker mutation.
Cell Discov 12 ? ? (2026)
PMID: 42957638 DOI: 10.1038/s41421-026-00936-y
Primary Citation of related structures
25CG
Feedback Form
Name
Email
Institute
Feedback